ONCOLOGY

We offer a broad range of human biospecimens preserved as fresh, frozen or formalin‑fixed paraffin‑embedded (FFPE) tissues, blood products and matched sets for biomarker studies. All specimens are annotated and quality‑assessed.

Oncology is a core therapeutic area for Global Biologics. We support cancer research across both solid tumors and hematological malignancies by providing access to fresh, frozen and FFPE tumor tissues as well as matched adjacent normal tissues, blood products and bone‑marrow samples. Our established clinical networks collect specimens prospectively across a range of tumor types and disease stages, and we maintain archives of de‑identified oncology specimens.

Key oncology offerings include:

  • Comprehensive tissue sets. The Cancer QUADRUPLET™ Tissue Set pairs fresh and snap‑frozen tumor tissue with adjacent normal tissue, FFPE samples, serum/plasma and whole blood controls to support integrative analyses.

  • Hematologic malignancy collections. We provide snap‑frozen, bone‑marrow aspirates, marker‑specific cell subsets, and matched serum/plasma for studies of leukemias, lymphomas and other blood cancers.

  • Prospective and longitudinal sampling. Through our networks, we can collect specimens at defined clinical time points, including pre‑ and post‑treatment, enabling longitudinal biomarker studies. When collecting these specimens we monitor pre‑analytical variables—such as warm and cold ischemia times and fixation duration—because tissue quality is closely tied to processing conditions.

Whether you need archived tumor samples, matched blood products or custom prospective collections, our oncology services provide the high‑quality biospecimens and regulatory compliance necessary for successful translational research.

Blood and Bone Marrow

  • Hematologic Oncology and Solid Oncology - plasma and bone‑marrow aspirates collected from hematologic and solid‑tumor patients.

  • Inflammation and Autoimmune Disease – blood‑derived products from inflammatory disorders such as rheumatoid arthritis.

  • Normal Control Samples – matched blood products from healthy donors.

Treatment‑Relevant Serum

We maintain banked collections of serum sets from oncology patients and can collect prospectively under NCCN Oncology Treatment Guidelines. Serum collections are available such as:

  • Single‑course sets – samples collected from patients following one treatment course.

  • Multiple‑course sets – serial samples collected over multiple immunotherapy, chemotherapy or radiation courses.

In most cases, serum is obtained during initial diagnosis before clinical intervention; however, we can procure specimens meeting specific inclusion or exclusion criteria. Proper quality management ensures that pre‑analytical variables are controlled, as variations in sample handling or freeze‑thaw cycles can affect downstream analyses.

Human Therapeutic Plasma

Global Biologics provides human therapeutic plasma for oncology and inflammatory diseases from banked samples or prospective collections. Please contact us for availability.

Biospecimen Sets

Our biospecimen sets provide matched tissues and blood components for comprehensive analyses.

  • Oncology – Solid Tumors (Cancer QUADRUPLET™ Tissue Set)

    • Fresh tumor tissue (surgical specimen)

    • Snap‑frozen tumor tissue

    • Snap‑frozen adjacent normal tissue

    • FFPE tumor tissue and FFPE adjacent normal tissue

    • Cancer serum (pre‑surgery) and plasma

    • Whole blood (normal DNA control)

    • Whole blood in RNA PaxGene tubes

  • Hematological Malignancies

    • Cancer serum and plasma (same‑day collection)

    • Bone‑marrow aspirate and snap‑frozen bone marrow (including trephine biopsy)

    • Viable bone‑marrow mononuclear cells and marker‑specific subsets

  • Rheumatoid Arthritis

    • Snap‑frozen synovial tissue biopsies with matched FFPE biopsies

    • Synovial fluid (matched or unmatched)

    • Frozen liquid fractions and viable cells

    • Matching serum and plasma (same‑day collection)

    • Whole blood in RNA PaxGene tubes

      These sets can be customized to fit individual project requirements.